己酰-CoA的β氧化为丁酰-CoA
中文名称
通路描述
β-氧化螺旋的第六次通过以饱和脂肪酸己酰-CoA为起点，产生丁酰-CoA。需要四个酶促步骤，首先由短链酰-CoA脱氢酶（SCAD）活性开始，随后由crotonase的烯酰-CoA水合酶活性，由短链3-羟基酰-CoA脱氢酶（SCHAD）的3-羟基酰-CoA脱氢酶活性，最后由线粒体膜相关三功能蛋白中的酮酰-CoA硫酶活性完成。
英文描述
Beta oxidation of hexanoyl-CoA to butanoyl-CoA The sixth pass through the beta-oxidation spiral picks up where the last left off with the saturated fatty acid hexanoyl-CoA and produces butanoyl-CoA. Four enzymatic steps are required starting with SCAD CoA dehydrogenase (Short Chain) activity, followed by the enoyl-CoA hydratase activity of crotonase, the 3-hydroxyacyl-CoA dehydrogenase activity of the short chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD), and completed by the ketoacyl-CoA thiolase activity, present in the mitochondrial membrane associated trifunctional protein.
所含基因
5 个基因