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Insulin receptor recycling

Reactome ID: R-HSA-77387

中文名称

胰岛素受体回收

通路描述

由内体酸化触发,胰岛素从受体上解离并被降解。受体脱磷酸化并重新整合到细胞膜,准备好再次被胰岛素分子激活。
英文描述
Insulin receptor recycling Triggered by acidification of the endosome, insulin dissociates from the receptor and is degraded. The receptor is dephosphorylated and re-integrated into the plasma membrane, ready to be activated again by the binding of insulin molecules.

所含基因

30 个基因