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VLDLR internalisation and degradation

Reactome ID: R-HSA-8866427

中文名称

VLDLR 内吞和降解

通路描述

VLDLR 内吞和降解的步骤涉及 PCSK9 诱导的 proprotein convertase 的降解过程(Poirier et al. 2008)。该降解过程的速率在决定血液中的脂蛋白清除效率方面起着临床显著的作用。
英文描述
VLDLR internalisation and degradation The steps involved in proprotein convertase PCSK9-induced degradation of VLDLR are described here (Poirier et al. 2008). The rate of this catabolic process plays a clinically significant role in determining the efficiency of lipoprotein clearance from the blood.

所含基因

16 个基因