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GABA synthesis

Reactome ID: R-HSA-888568

中文名称

GABA 合成

通路描述

由谷氨酸脱羧酶 GAD65 和 GAD67 合成,其中 GAD65 合成的 GABA 主要装载于突触囊泡以介导神经传递。
英文描述
GABA synthesis GABA synthesized uniquely by two forms of glutamate decarboxylases, GAD65 and GAD67, that are functionally distinct and have different co-factor requirements. GAD65 is functionally linked to VGAT, the GABA transporter and selectively GABA synthesized by GAD65 is preferably loaded into the synaptic vesicles. GABA synthesized by GAD67 may be used for functions other than nuerotransmission.

所含基因

1 个基因