JAK-STAT 信号通路在干扰素 -12 刺激后的基因和蛋白质表达
中文名称
通路描述
使用人脐带血 CD4(+) T 细胞进行的实验显示，在干扰素 -12 刺激后，分别上调和下调了 22 个蛋白质位点和 20 个蛋白质位点（Rosengren 等 2005）。鉴定的上调蛋白质包括：BOLA2、PSME2、MTAP、CA1、GSTA2、RALA、CNN2、CFL1、TCP1、HNRNPDL、MIF、AIP、SOD1、PPIA 和 PDCD4。鉴定的下调蛋白质包括：ANXA2、RPLP0、CAPZA1、SOD2、SNRPA1、LMNB1、LCP1、HSPA9、SERPINB2、HNRNPF、TALDO1、PAK2、TCP1、HNRNPA2B1、MSN、PITPNA、ARF1、SOD2、ANXA2、CDC42、RAP1B 和 GSTO1。
英文描述
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Experiments using human cord blood CD4(+) T cells show 22 protein spots and 20 protein spots, upregulated and downregulated proteins respectively, following Interleukin-12 stimulation (Rosengren et.al, 2005). The identified upregulated proteins are: BOLA2, PSME2, MTAP, CA1, GSTA2, RALA, CNN2, CFL1, TCP1, HNRNPDL, MIF, AIP, SOD1, PPIA and PDCD4.
And the identified downregulated proteins are:
ANXA2, RPLP0, CAPZA1, SOD2, SNRPA1, LMNB1, LCP1, HSPA9, SERPINB2, HNRNPF, TALDO1, PAK2, TCP1, HNRNPA2B1, MSN, PITPNA, ARF1, SOD2, ANXA2, CDC42, RAP1B and GSTO1.
And the identified downregulated proteins are:
ANXA2, RPLP0, CAPZA1, SOD2, SNRPA1, LMNB1, LCP1, HSPA9, SERPINB2, HNRNPF, TALDO1, PAK2, TCP1, HNRNPA2B1, MSN, PITPNA, ARF1, SOD2, ANXA2, CDC42, RAP1B and GSTO1.
所含基因
37 个基因