乳糜微粒组装
中文名称
通路描述
乳糜微粒将来自小肠的膳食脂质衍生的甘油三酯、磷脂和胆固醇转运至身体其他组织。每个乳糜微粒围绕单个apolipoprotein B-48分子组装而成(Phillips et al. 1997)。当该粒子离开肠道进入淋巴循环时,它与超过20万个甘油三酯分子、约3.5万个磷脂分子、约1.1万个胆固醇酯分子、约8000个游离胆固醇分子、60个apolipoprotein A-I分子、15个apolipoprotein A-IV分子以及apolipoprotein A-II分子复合物(Bhattacharya and Redgrave 1981)。
英文描述
Chylomicron assembly Chylomicrons transport triacylglycerol, phospholipid, and cholesterol derived from dietary lipid from the small intestine to other tissues of the body. Each chylomicron assembles around a single molecule of apolipoprotein B-48 (Phillips et al. 1997) which at the time the particle leaves the intestine and enters the lymphatic circulation is complexed with >200,000 molecules of triacylglycerol (TG), ~35,000 of phospholipid, ~11,000 of cholesterol ester, ~8,000 of free cholesterol, ~60 copies of apolipoprotein A-I, ~15 copies of apolipoprotein A-IV, and copies of apolipoprotein A-II (Bhattacharya and Redgrave 1981).
所含基因
10 个基因