肠道六糖吸收
中文名称
通路描述
六糖，特别是果糖、葡萄糖和半乳糖，在小肠腔内由膳食碳水化合物分解产生，被小肠绒毛上皮细胞摄取，并从它们释放到血液中。进入上皮细胞的摄取由位于细胞微绒毛表面的两种转运体介导。SLC5A1，也称为 SGLT1，介导钠离子和葡萄糖及半乳糖的协同运输，SLC2A5，也称为 GLUT5，介导果糖摄取（Wright 1998）。四聚体 SLC2A2，也称为 GLUT2，定位于上皮细胞的基底侧表面，介导这些六糖释放到血液中（Kellett & Brot-Laroche 2005; Wright et al. 2004）。
英文描述
Intestinal hexose absorption Hexoses, notably fructose, glucose, and galactose generated in the lumen of the small intestine by breakdown of dietary carbohydrate, are taken up by enterocytes lining the microvilli of the small intestine and released from them into the blood. Uptake into enterocytes is mediated by two transporters localized on the luminal surfaces of the cells. SLC5A1, also known as SGLT1, mediates the co-transport of sodium ions and glucose and galactose, and SLC2A5, also known as GLUT5, mediates fructose uptake (Wright 1998). Tetrameric SLC2A2, also known as GLUT2, localized on the basolateral surfaces of enterocytes, mediates the release of these hexoses into the blood (Kellett & Brot-Laroche 2005; Wright et al. 2004).
所含基因
4 个基因