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Transferrin endocytosis and recycling

Reactome ID: R-HSA-917977

中文名称

转铁蛋白内吞和回收

通路描述

铁负载的转铁蛋白/受体复合物的内吞,在酸化后,导致铁与其扩散出囊泡。内囊泡不与溶酶体融合,而是将其内容物回收回细胞表面,随后转铁蛋白与其受体分离(Dautry-Varsat, 1986)。
英文描述
Transferrin endocytosis and recycling Endocytosis of iron loaded transferrin/receptor complex leads, after acidification of the endosome, to the separation of iron and its diffusion out of the vesicle. The endosome is not fused with a lysosome but recycles its content back to the cell surface where soon transferrin dissociates from its receptor (Dautry-Varsat, 1986).

所含基因

30 个基因