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Lipophagy

Reactome ID: R-HSA-9613354

中文名称

脂溶食作用

通路描述

储存于脂滴中的甘油三酯在营养饥饿时被水解以释放脂肪酸作为能量。脂滴中的内容物可能不同,但都覆盖着一种称为 perilipin 的保护性蛋白。当这种蛋白被降解时,脂滴与自噬成分结合并分解为脂肪酸(Ward C 等,2016;Schulze R J 等,2017)。此过程称为脂溶食作用(Singh R 等,2009)。
英文描述
Lipophagy Triglycerides stored in lipid droplets are hydrolysed under nutrient starvation to release fatty acids for energy. The content of lipid droplets may vary but they are all coated with a protective protein called perilipin. When this protein is degraded, lipid droplets associate with autophagic components and breakdown into fatty acids (Ward C et al. 2016, Schulze R J et al. 2017). This process is termed as lipophagy (Singh R et al. 2009).

所含基因

9 个基因