蛋白质羟基化
中文名称
通路描述
该通路将 2-氧代谷氨酸（2-OG）依赖性氧合酶介导的反应归为一类，这些反应针对脯氨酸、赖氨酸、天冬酰胺、精氨酸、天冬氨酸和半胱氨酸残基，这些蛋白质具有不同的结构，其效应可能调节转录和翻译（Herr 和 Hausinger 2018; Markolovic 等人 2015; Stoehr 等人 2016; Zurlo 等人 2016）
英文描述
Protein hydroxylation This pathway groups reactions mediated by 2-OG (2-oxoglutarate)-dependent oxygenases that target proline, lysine, asparagine, arginine, aspartate, and histidine residues of diverse proteins, with effects that potentially modulate transcription and translation (Herr & Hausinger 2018; Markolovic et al. 2015; Stoehr et al. 2016; Zurlo et al. 2016).The roles of members of this enzyme family in collagen assembly are annotated separately in pathway R-HSA-1650814, "Collagen biosynthesis and modifying enzymes".
所含基因
20 个基因