NEIL3介导的 ICLs 解离
中文名称
通路描述
NEIL3 的 DNA 糖基酶活性参与 psolaren 诱导的间链交联（ICLs）以及无 Fanconia 贫血（FA）途径中由缺碱基位点诱导的 ICLs 的解离（unhooking）（Semlow et al. 2016, Martin et al. 2017）。
英文描述
NEIL3-mediated resolution of ICLs DNA glycosylase activity of NEIL3 is involved in resolution (unhooking) of psolaren-induced interstrand crosslinks (ICLs), as well as abasic site-induced ICLs (AP-ICLs) in a Fanconia anemia (FA) pathway-independent fashion (Semlow et al. 2016, Martin et al. 2017).
所含基因
1 个基因