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Action of antimicrobials

Reactome ID: R-HSA-9638771

中文名称

抗菌剂的作用

通路描述

抗菌化合物杀死微生物或抑制其生长,要么在宿主内,要么在皮肤表面(消毒剂),要么在环境中(消毒剂)。在宿主内,它们以靶共生体命名,例如抗生素、抗真菌剂和抗寄生虫药。只需永久停止共生体的必需途径即可杀死它。广谱抗菌剂通常靶向保守途径,如蛋白质合成或细胞壁构建,以影响整个分类群(Arenz & Wilson 2016, Barry et al. 2007, Green 2002)。
英文描述
Action of antimicrobials Antimicrobial compounds kill microorganisms or inhibit their growth, either in the host, outside on the skin (antiseptics), or in the environment (disinfectants). In the host they are named after the target symbiont, for example antibiotics, antifungals, and antiparasitics. It suffices to permanently stop an essential pathway in the symbiont to kill it. Broad spectrum antimicrobials usually target a conserved pathway like protein synthesis or cell wall construction, in order to affect a whole taxonomic group (Arenz & Wilson 2016, Barry et al. 2007, Green 2002).

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