RAS 加工
中文名称
通路描述
RAS 蛋白在成熟过程中经历多个加工步骤,包括泛素化、羧基端切割和羧甲基化等。这些步骤对于其膜定位和功能至关重要,最终使其能够激活 RAF(综述见 Gysin et al, 2011; Ahearn et al, 2018)。
英文描述
RAS processing RAS proteins undergo several processing steps during maturation including farnesylation, carboxy-terminal cleavage and carboxymethylation, among others. These steps are required for their membrane localization and function and ultimately for their ability to activate RAF (reviewed in Gysin et al, 2011; Ahearn et al, 2018).
所含基因
23 个基因