高尔基体相关囊泡生物发生
中文名称
通路描述
已合成、加工并分选的最终蛋白质最终到达分泌途径的最后步骤。该途径不仅负责从细胞分泌的蛋白质，还负责ER、高尔基体和溶酶体腔内的酶及其他驻留蛋白，以及运输在囊泡膜中的整合蛋白。
英文描述
Signaling downstream of RAS mutants Disease-causing mutations in RAS favour the active RAS:GTP bound form and yield constitutively active forms of the protein (reviewed in Prior et al, 2011; Maertens and Cichowski, 2014). Mutations in RAS contribute to cellular proliferation, transformation and survival by activating the MAPK signaling pathway, the AKT pathway and the RAL GDS pathway, among others (reviewed in Stephen et al, 2014; Pylayeva-Gupta et al, 2011)
所含基因
41 个基因