各种N-糖基生物合成
中文名称
通路描述
N-糖基生物合成在ER和Golgi膜的外表面组装复杂的分支寡糖链，以与蛋白质的天冬酰胺残基结合；对于蛋白质折叠、细胞间识别、免疫反应和激素信号传导至关重要。
英文描述
Drug-mediated inhibition of ERBB2 signaling Signaling by ERBB2 can be pharmacologically inhibited with tyrosine kinase inhibitors (TKIs) (Nelson and Fry 2001, Xia et al. 2002, Wood et al. 2004, Rabindran et al. 2004, Gandreau et al. 2007, Jani et al. 2007, Li et al. 2008, Hichkinson et al. 2010, Traxler et al. 2014, Hanker et al. 2017), and therapeutic antibodies, such as trastuzumab (Hudziak et al. 1989, Carter et al. 1992, Pickl and Ries 2009, Maadi et al. 2018) and pertuzumab (Franklin et al. 2004).
所含基因
4 个基因