缺陷 F8 与细胞膜结合
中文名称
通路描述
Reactome 事件描述了因 HA 相关 FVIII 变体 (如 A2220P, A2220del 和 Q2330P) 导致凝血酶激活的 FVIIIa 蛋白与磷脂膜表面相互作用缺陷。
英文描述
Defective F8 binding to the cell membrane The Reactome event describes the defective interaction between the thrombin-activated FVIIIa protein and phospholipid membrane surfaces caused by hemophilia A-associated FVIII variants, such as A2220P, A2220del and Q2330P.
所含基因
1 个基因