NFE2L2 调控戊糖磷酸途径基因
中文名称
通路描述
NFE2L2 调控戊糖磷酸途径基因，该通路代表由 NFE2L2（NRF2）调控的戊糖磷酸途径基因。NFE2L2 指导与戊糖磷酸途径相关的基因转录，有助于代谢途径应对氧化应激，并在癌症进展中发挥重要作用。
英文描述
FLT3 signaling by CBL mutants Missense and splicing mutants have been identified in the E3 ubiquitin ligase CBL in a number of cancers including acute and chronic myeloid leukemias, among others. These cancers show elevated signaling through FLT3 as a result of impaired CBL-mediated downregulation of the receptor (Sargin et al, 2007; Reindl et al, 2009; Caligiuri et al, 2007; Abbas et al, 2008).
所含基因
5 个基因