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SHOC2 M1731 mutant abolishes MRAS complex function

Reactome ID: R-HSA-9726840

中文名称

SHOC2 M1731 突变使 MRAS 复合物功能丧失

通路描述

该通路描述了 SHOC2 功能丧失突变对 RAF 激活的影响(Rodriguez-Viciano 等,2006;Hannig 等,2014)。SHOC2 的丧失和获得功能突变如何共同促进 RAF 通路激活尚待阐明。
英文描述
SHOC2 M1731 mutant abolishes MRAS complex function This pathway describes the effect of a loss-of-function mutation in SHOC2 on RAF activation (Rodriguez-Viciano et al, 2006; Hannig et al, 2014). How both loss- and gain-of-function SHOC2 mutants can contribute to RAF pathway activation remains to be elucidated.

所含基因

4 个基因