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Retinoid metabolism and transport

Reactome ID: R-HSA-975634

中文名称

视黄醇代谢和转运

通路描述

维生素 A(全反式视黄醇)必须从植物中的胡萝卜素或动物食品中的视黄醇酯摄取。最显著的胡萝卜素是α-胡萝卜素、番茄红素、叶黄素、β-隐黄质和特别β-胡萝卜素。摄取后,它们主要被分解为视黄醇。视黄醇酯像其他脂肪一样水解。在肠细胞中,视黄醇与视黄醇结合蛋白(RBP)结合。从肠细胞到肝脏的转运通过乳糜微粒进行(Harrison & Hussain 2001, Harrison 2005)。
英文描述
Retinoid metabolism and transport Vitamin A (all-trans-retinol) must be taken up, either as carotenes from plants, or as retinyl esters from animal food. The most prominent carotenes are alpha-carotene, lycopene, lutein, beta-cryptoxanthine, and especially beta-carotene. After uptake they are mostly broken down to retinal. Retinyl esters are hydrolysed like other fats. In enterocytes, retinoids bind to retinol-binding protein (RBP). Transport from enterocytes to the liver happens via chylomicrons (Harrison & Hussain 2001, Harrison 2005).

所含基因

34 个基因