微RNA对CDH11 mRNA翻译的调节
中文名称
通路描述
若干微RNA涉及CDH11基因表达的转录后调节。该图仅显示被报道下调CDH11 mRNA和/或蛋白水平的微RNA，至少有两项研究，其中至少一项提供人类证据，至少一项提供通过荧光素酶报告实验和/或形成微RNA-mRNA复合物作为机制证据的说明。有关微RNA注释标准的更详细描述请参见Huntley等, 2016。
以下CDH11靶向微RNA得到实验证据的强烈支持，并在图中直接显示：
miR-200c-3p（Luo等, 2013; Van der Goten等, 2014）
miR-451a（Yamada等, 2018; Wang等, 2020; Wang等, 2021）
以下微RNA可能靶向CDH11，但需要更多证据以直接表示它们：
miR-103-2-5p（Gao等, 2020）
miR-127-3p（Dong等, 2021）
miR-148-5p（Kawagoe等, 2020）
以下CDH11靶向微RNA得到实验证据的强烈支持，并在图中直接显示：
miR-200c-3p（Luo等, 2013; Van der Goten等, 2014）
miR-451a（Yamada等, 2018; Wang等, 2020; Wang等, 2021）
以下微RNA可能靶向CDH11，但需要更多证据以直接表示它们：
miR-103-2-5p（Gao等, 2020）
miR-127-3p（Dong等, 2021）
miR-148-5p（Kawagoe等, 2020）
英文描述
Regulation of CDH11 mRNA translation by microRNAs Several microRNAs are implicated in posttranscriptional regulation of CDH11 gene expression. The diagram only shows microRNAs reported to downregulate CDH11 mRNA and/or protein levels by at least 2 studies, with at least one study providing human evidence, and at least one study providing mechanistic evidence in the form of luciferase reporter assay and/or formation of the microRNA-mRNA complex. For a more detailed description of criteria for microRNA annotation please refer to Huntely et al. 2016.
The following CDH11-targeting microRNAs are strongly supported by experimental evidence and directly shown in the diagram:
miR-200c-3p (Luo et al. 2013; Van der Goten et al. 2014)
miR-451a (Yamada et al. 2018; Wang et al. 2020; Wang et al. 2021)
The following microRNAs probably target CDH11, but additional evidence is needed to directly represent them in the diagram:
miR-103-2-5p (Gao et al. 2020)
miR-127-3p (Dong et al. 2021)
miR-148-5p (Kawagoe et al. 2020)
The following CDH11-targeting microRNAs are strongly supported by experimental evidence and directly shown in the diagram:
miR-200c-3p (Luo et al. 2013; Van der Goten et al. 2014)
miR-451a (Yamada et al. 2018; Wang et al. 2020; Wang et al. 2021)
The following microRNAs probably target CDH11, but additional evidence is needed to directly represent them in the diagram:
miR-103-2-5p (Gao et al. 2020)
miR-127-3p (Dong et al. 2021)
miR-148-5p (Kawagoe et al. 2020)
所含基因
9 个基因