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Ion channel transport

Reactome ID: R-HSA-983712

中文名称

离子通道运输

通路描述

离子通道介导细胞质膜上离子的流动。它们是整合膜蛋白,通常是蛋白质多聚体,当在膜上排列时,形成离子流动的孔道。存在不同类型的离子通道。P 型 ATP 酶通过构象变化转运离子。配体门控离子通道像门一样运作,由化学信号打开或关闭。电压门控离子通道由膜上的电势差变化激活(Purves, 2001; Kuhlbrandt, 2004)。
英文描述
Ion channel transport Ion channels mediate the flow of ions across the plasma membrane of cells. They are integral membrane proteins, typically a multimer of proteins, which, when arranged in the membrane, create a pore for the flow of ions. There are different types of ion channels. P-type ATPases undergo conformational changes to translocate ions. Ligand-gated ion channels operate like a gate, opened or closed by a chemical signal. Voltage-gated ion channels are activated by changes in electrical potential difference at the membrane (Purves, 2001; Kuhlbrandt, 2004).

所含基因

24 个基因