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TGFBR3 regulates activin signaling

Reactome ID: R-HSA-9839406

中文名称

TGFBR3 调节成纤维细胞生长因子信号通路

通路描述

该子通路描述了 TGFBR3 对成纤维细胞生长因子信号通路的调节。TGFBR3 与 Inhibin A 结合,Inhibin A 也是 TGFBR3 的配体,通过竞争性结合 ACVR2A 受体和 BMPRII 抑制成纤维细胞生长因子/BMP 信号 (Esparza-Lopez et al., 2001, Lewis et al., 2000, Wiater et al., 2003)。
英文描述
TGFBR3 regulates activin signaling This subpathway describes the regulation of activin signaling by TGFBR3. TGFBR3 binds with Inhibin A, which is also a ligand for TGFBR3 and inhibits activin/BMP signaling by binding competititively to ACVR2A receptor and BMPRII (Esparza-Lopez et al., 2001, Lewis et al., 2000, Wiater et al., 2003).

所含基因

3 个基因