胰腺导管细胞发育谱系
中文名称
通路描述
导管上皮细胞以单层形式覆盖胰腺导管，随着导管增大从立方体，到低柱状，到高柱状上皮细胞改变形状（Liggitt和Dintzis，《胰腺》，第241-250页）。导管上皮细胞可能在顶表面具有微绒毛或纤毛（Liggitt和Dintzis，《胰腺》，第241-250页）。除了导管上皮细胞外，主要胰腺导管有时包括杯状细胞（Liggitt和Dintzis，《胰腺》，第241-250页）。
英文描述
Developmental Lineage of Pancreatic Ductal Cells Ductal epithelial cells line the pancreatic ducts in a single layer, changing the shape as ducts increase in size from cuboidal, through low columnar, to high columnar epithelium (Liggitt and Dintzis, âPancreasâ, pp. 241-250). Ductal epithelial cells may have cilia or microvilli on their apical surface (Liggitt and Dintzis, âPancreasâ, pp. 241-250). Besides ductal epithelial cells, main pancreatic ducts sometimes include goblet cells (Liggitt and Dintzis, âPancreasâ, pp. 241-250).Ductal epithelial cells develop from bipotent pancreatic trunk progenitor cells, which also give rise to endocrine progenitors and are derived from the primary multipotent pancreatic progenitor cells (reviewed in Shih et al. 2013, Jennings et al. 2015).
所含基因
44 个基因