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Formation of the polybromo-BAF (pBAF) complex

Reactome ID: R-HSA-9933939

中文名称

多溴化 BAF 复合物的形成

通路描述

哺乳动物 pBAF (多溴化 BAF) 复合物是酿酒酵母 RSC (染色质结构重塑) 复合物的同旁异源物 (Xue 等人,2000; 综述于 Mittal 和 Roberts, 2020; Cenik 和 Shilatifard, 2021; Wang 和 Tang, 2023)。哺乳动物 pBAF 与 cBAF 共享许多核心亚基,但通过 ARID2 取代 ARID1A 或 B 而有所区别 (Wang, Cote 等人,1996; Wang, Xue 等人,1996; Xue 等人,2000; Lemon 等人,2001; Yan 等人,2005; Mashtalir 等人,2018; Mashtalir 等人,2020; de Castro 2017; Wang 等人,2022; Yuan 等人,2022; Feoktistov 等人,2023)。pBAF 还包含独特的亚基 PHF10, BRD7 和 PBRM (Kaeser 等人,2008; Mashtalir 等人,2018; Mashtalir 等人,2020; Wang 等人,2022; Yuan 等人,2022; 综述于 Mittal 和 Roberts, 2020; Cenik 和 Shilatifard, 2021; Innis 和 Cabot, 2020)。
英文描述
Formation of the polybromo-BAF (pBAF) complex Mammalian pBAF (polybromo-associated BAF) complex is paralogous to the RSC (remodel the structure of chromatin) complex of S. cerevisiae (Xue et al, 2000; reviewed in Mittal and Roberts, 2020; Cenik and Shilatifard, 2021; Wang and Tang, 2023). Mammalian pBAF shares many of the same core subunits as cBAF, but is distinguished by the presence of ARID2 in place of ARID1A or B (Wang, Cote et al, 1996; Wang, Xue et al, 1996; Xue et al, 2000; Lemon et al, 2001; Yan et al, 2005; Mashtalir et al, 2018; Mashtalir et al, 2020; de Castro 2017; Wang et al, 2022; Yuan et al, 2022; Feoktistov et al, 2023). pBAF also contains unique subunits PHF10, BRD7 and PBRM (Kaeser et al, 2008; Mashtalir et al, 2018; Mashtalir et al, 2020; Wang et al, 2022; Yuan et al, 2022; reviewed in Mittal and Roberts, 2020; Cenik and Shilatifard, 2021; Innis and Cabot, 2020).

所含基因

18 个基因