脂肪酸生物合成
中文名称
通路描述
从头脂肪酸生物合成将乙酰-CoA 转化为长链饱和脂肪酸,主要是棕榈酸(C16:0),通过涉及乙酰-CoA 羧化酶产生丙二酰-CoA 和脂肪酸合酶复合物的多步过程。该途径受胰岛素、草酰乙酸和亮氨酸的高度调节。
英文描述
De novo fatty acid biosynthesis converts acetyl-CoA into long-chain saturated fatty acids, primarily palmitate (C16:0), through a multi-step process involving the key enzymes acetyl-CoA carboxylase for malonyl-CoA production and the fatty acid synthase complex. This pathway is highly regulated by insulin, citrate, and leucine.
所含基因
18 个基因