脂肪酸降解
中文名称
通路描述
脂肪酸β-氧化通过涉及活化、肉碱穿梭运输、酰基-CoA脱氢酶氧化、水化和硫解的四步循环过程,将长链脂肪酸分解为乙酰-CoA 的二碳单元。它发生在大多数链长的线粒体基质中,以及长链脂肪酸的过氧化物酶体中。
英文描述
Fatty acid beta-oxidation breaks down long-chain fatty acids into two-carbon units of acetyl-CoA through a cyclic four-step process involving activation, transport via the carnitine shuttle, oxidation by acyl-CoA dehydrogenase, hydration, and thiolysis. It occurs in both mitochondrial matrix for most chain lengths and peroxisomes for very-long-chain fatty acids.
所含基因
43 个基因