鞘脂代谢
中文名称
通路描述
鞘脂代谢涉及从 Serine 和棕榈酰-CoA 合成鞘氨醇，转化为 Ceramide（一种中心活性脂质），然后分支为复杂的糖鞘脂或降解；Ceramide 是凋亡、细胞衰老和应激反应中的关键信号分子。
英文描述
Sphingolipid metabolism involves synthesis of sphingosine from serine and palmitoyl-CoA, conversion to ceramide (a central bioactive lipid), then branching into complex glycosphingolipids or degradation; ceramide is a key signaling molecule in apoptosis, cell senescence, and stress response.
所含基因
55 个基因
ACER1
ACER2
ACER3
ARSA
ASAH1
ASAH2
B4GALNT1
B4GALT5
B4GALT6
CERK
CERS1
CERS2
CERS3
CERS4
CERS5
CERS6
DEGS1
DEGS2
ENPP7
GAL3ST1
GALC
GBA1
GBA2
GLA
GLB1
GM2A
HEXA
HEXB
KDSR
NEU1
NEU2
NEU3
NEU4
PLPP1
PLPP2
PLPP3
PSAP
PSAPL1
SAMD8
SGMS1
SGMS2
SGPL1
SGPP1
SGPP2
SMPD1
SMPD2
SMPD3
SMPD4
SPHK1
SPHK2
SPTLC1
SPTLC2
SPTLC3
UGCG
UGT8