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Folate biosynthesis

KEGG ID: hsa00790

中文名称

叶酸生物合成

通路描述

叶酸生物合成(在微生物中)通过叶酸途径产生四氢叶酸:二氢叶酸合成酶受磺胺类抗生素抑制,二氢叶酸还原酶被甲氨蝶呤靶向;人类从饮食中获取叶酸,但保留补救途径。
英文描述
Folate biosynthesis (in microbes) produces tetrahydrofolate through the folate pathway: dihydropteroate synthase is inhibited by sulfonamide antibiotics, and dihydrofolate reductase is targeted by methotrexate; humans acquire folate from diet but retain salvage pathways.

所含基因

28 个基因