蛋白质分泌
中文名称
通路描述
蛋白质分泌是指蛋白质从细胞质主动转运到细胞外或革兰氏阴性菌的周质空间的过程。Sec 依赖途径是通用的蛋白质分泌系统，将新合成的蛋白质转运进或穿过细胞膜。转运通道是由一个保守的三聚体膜蛋白复合物形成的，称为 Sec61/SecY 复合物。双丙氨酸转运（Tat）途径是另一种蛋白质转运系统，在细菌、古菌和叶绿体中转运折叠的蛋白质。许多 Tat 系统由三个功能不同的膜蛋白组成，即 TatA、TatB 和 TatC，但 TatA 和 TatE 似乎具有重叠的功能，其中 TatA 起着最主要的作用。
英文描述
The protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the general protein export system that transports newly synthesized proteins into or across the cell membrane. The translocation channel is formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex. The twin-arginine translocation (Tat) pathway is another protein transport system that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems comprise three functionally different membrane proteins, TatA, TatB, and TatC, but TatA and TatE seem to have overlapping functions, with TatA having by far the more important role.
所含基因
31 个基因