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Neuroactive ligand-receptor interaction

KEGG ID: hsa04080

中文名称

神经活性配体 - 受体相互作用

通路描述

神经活性配体 - 受体相互作用：神经递质（乙酰胆碱、多巴胺、血清素、GABA、谷氨酸、组胺）与其特异性受体结合，这些受体是离子通道或GPCR，介导突触传递并调节中枢和外周神经系统中的神经元兴奋性。
英文描述
Neuroactive ligand-receptor interaction: neurotransmitters (acetylcholine, dopamine, serotonin, GABA, glutamate, histamine) bind to their specific receptors — ionotropic channels or GPCRs — mediating synaptic transmission and modulating neuronal excitability in the central and peripheral nervous systems.

所含基因

370 个基因
ADCYAP1 ADCYAP1R1 ADM ADM2 ADORA1 ADORA2A ADORA2B ADORA3 ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 AGT AGTR1 AGTR2 APELA APLN APLNR AVP AVPR1A AVPR1B AVPR2 BDKRB1 BDKRB2 BRS3 C3 C3AR1 C5 C5AR1 CALCA CALCB CALCR CALCRL CCK CCKAR CCKBR CGA CHRFAM7A CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CHRNA1 CHRNA10 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB1 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG CNR1 CNR2 CORT CRH CRHR1 CRHR2 CSH1 CSH2 CSHL1 CTSG CYSLTR1 CYSLTR2 DRD1 DRD2 DRD3 DRD4 DRD5 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 FPR1 FPR2 FPR3 FSHB FSHR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GABRR1 GABRR2 GABRR3 GAL GALP GALR1 GALR2 GALR3 GCG GCGR GH1 GH2 GHR GHRH GHRHR GHRL GHSR GIP GIPR GLP1R GLP2R GLRA1 GLRA2 GLRA3 GLRB GNRH1 GNRH2 GNRHR GPHA2 GPHB5 GPR156 GPR35 GPR50 GPR83 GRIA1 GRIA2 GRIA3 GRIA4 GRID1 GRID2 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A GRIN3B GRM1 GRM2 GRM3 GRM4 GRM5 GRM6 GRM7 GRM8 GRP GRPR GZMA HCRT HCRTR1 HCRTR2 HRH1 HRH2 HRH3 HRH4 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 IAPP INSL3 INSL5 KISS1 KISS1R KNG1 LEP LEPR LHB LHCGR LPAR1 LPAR2 LPAR3 LPAR4 LPAR6 LTB4R LTB4R2 LYNX1 LYPD6 LYPD6B MAS1 MC1R MC2R MC3R MC4R MC5R MCHR1 MCHR2 MLN MLNR MTNR1A MTNR1B NMB NMBR NMS NMU NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPFF NPFFR1 NPFFR2 NPS NPSR1 NPVF NPW NPY NPY1R NPY2R NPY4R NPY4R2 NPY5R NR3C1 NTS NTSR1 NTSR2 OGFR OGFRL1 OPRD1 OPRK1 OPRL1 OPRM1 OXT OXTR P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2RY1 P2RY10 P2RY11 P2RY13 P2RY14 P2RY2 P2RY4 P2RY6 P2RY8 PAQR6 PAQR9 PATE1 PATE2 PATE3 PATE4 PDYN PENK PGRMC1 PGRMC2 PLG PMCH PNOC POMC PPY PRL PRLH PRLHR PRLR PRSS1 PRSS2 PRSS3 PTAFR PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR PTH PTH1R PTH2 PTH2R PYY QRFP QRFPR RLN1 RLN2 RLN3 RXFP1 RXFP2 RXFP3 RXFP4 S1PR1 S1PR2 S1PR3 S1PR4 S1PR5 SCT SCTR SLURP1 SLURP2 SPX SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 TAAR1 TAAR2 TAAR5 TAAR6 TAAR8 TAAR9 TAC1 TAC3 TAC4 TACR1 TACR2 TACR3 TBXA2R THRA THRB TMEM97 TRH TRHR TRPV1 TSHB TSHR TSPO UCN UCN2 UCN3 UTS2 UTS2B UTS2R VGF VIP VIPR1 VIPR2