激素信号 - Pathway Database

中文名称

激素信号

通路描述

激素信号：通过肽激素（胰岛素、生长激素）和类固醇激素（雌激素、睾酮、皮质醇）介导的内分泌通信，这些激素作用于核受体；甲状腺激素结合TR-α/β；受体激活触发第二信使级联反应，调节代谢、生长、繁殖和应激反应。

英文描述

Hormone signaling: endocrine communication through peptide hormones (insulin, growth hormone), steroid hormones (estrogen, testosterone, cortisol) acting on nuclear receptors, and thyroid hormones binding TR-alpha/beta; receptor activation triggers second messenger cascades regulating metabolism, growth, reproduction, and stress responses.

所含基因

219 个基因

ACVR1 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADIPOQ ADIPOR1 ADIPOR2 ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 AGT AGTR1 AGTR2 AMH AMHR2 APPL1 AVP AVPR1A AVPR1B AVPR2 BMPR1A BMPR1B CALCA CALCB CALCR CCK CCKAR CCKBR CGA CRH CRHR1 CRHR2 CSH1 CSH2 CSHL1 DIO1 DIO2 DRD1 DRD2 DRD3 DRD4 DRD5 EPO EPOR ESR1 ESR2 FSHB FSHR GAST GCG GCGR GH1 GH2 GHR GHRH GHRHR GHRL GHSR GIP GIPR GLP1R GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR GPER1 GUCA2A GUCA2B GUCY2C HAMP HCRT HCRTR1 HCRTR2 HEPH HEPHL1 IAPP IGF1 IGF1R IGF2 INS INSR IRS1 IRS2 IRS4 ITGAV ITGB3 JAK2 LEP LEPR LHB LHCGR MC1R MC2R MC3R MC4R MC5R MCHR1 MCHR2 MLN MLNR MPL NOS1 NPPA NPPB NPPC NPR1 NPR2 NPR3 OPRD1 OPRK1 OPRL1 OPRM1 OXT OXTR P3R3URF-PIK3R3 PDYN PENK PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCB1 PLCB2 PLCB3 PLCB4 PMCH PNOC POMC PRKACA PRKACB PRKACG PRKG1 PRKG2 PRL PRLH PRLHR PRLR PTH PTH1R PTHLH RAMP1 RAMP2 RAMP3 RAPGEF3 RAPGEF4 RHOA SLC16A10 SLC16A2 SLC40A1 SLCO1C1 SMAD1 SMAD4 SMAD5 SMAD9 SRC SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 STAT3 STAT5A STAT5B STK11 THPO THRA THRB TRH TRHR TSHB TSHR UCN UCN2 UCN3 VIP VIPR1 VIPR2