钙粘蛋白信号

中文名称

钙粘蛋白信号

通路描述

钙粘蛋白是一类依赖钙的细胞间粘附蛋白的大超家族，是细胞相互作用、迁移和形态发生过程的时间和特异性决定的关键因素。许多钙粘蛋白通过组织化高度有序的连接复合物介导相邻细胞之间的机械耦合。除了粘附作用外，钙粘蛋白还作为信号平台，影响细胞运动、增殖和基因表达。

英文描述

Cadherins constitute a large superfamily of calcium-dependent cell-cell adhesion proteins that serve as critical determinants of the timing and specificity of cell interactions, migration, and morphogenetic processes. Many cadherins mediate mechanical coupling between adjacent cells by organizing highly ordered junctional complexes. Beyond their adhesive roles, cadherins act as signaling platforms that influence cell motility, proliferation, and gene expression.

所含基因

404 个基因

ABI2 ACTB ACTG1 ACTN1 ACTN4 ACTR2 ACTR3 ACTR3B ACTR3C ADAM10 AFDN AJUBA AMOTL1 AMOTL2 ANKRD6 APC APC2 APH1A APH1B ARHGAP35 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L ATN1 AXIN1 AXIN2 BRK1 CDC42 CDH1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17 CDH18 CDH19 CDH2 CDH20 CDH22 CDH23 CDH24 CDH26 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CELSR1 CELSR2 CELSR3 CHUK CIB2 CREBBP CSNK1A1 CSNK1A1L CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTNND1 CTNND2 CYFIP1 CYFIP2 DAAM1 DAAM2 DCHS1 DCHS2 DES DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSG4 DSP DVL1 DVL2 DVL3 EGFR ENAH EP300 ERBB2 ERBIN EVL FAT1 FAT2 FAT3 FAT4 FGFR1 FLT4 FMN1 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GABRR1 GABRR2 GABRR3 GJA1 GSK3B HRAS IGF1R IKBKB IKBKG JUP KDR KRAS KRT1 KRT10 KRT12 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT2 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33A KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT4 KRT40 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT86 KRT9 LATS1 LATS2 LEF1 LHFPL1 LHFPL2 LHFPL3 LHFPL4 LHFPL5 LHFPL6 LIMA1 LIMD1 LOC100653049 LRP5 LRP6 MAP2K1 MAP2K2 MAP2K3 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MET MOB1A MOB1B MPDZ MRAS MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO1H MYO7A NCKAP1 NCKAP1L NCSTN NF2 NFKB1 NFKBIA NRAS PALS1 PCDH1 PCDH10 PCDH11X PCDH11Y PCDH12 PCDH15 PCDH17 PCDH18 PCDH19 PCDH20 PCDH7 PCDH8 PCDH9 PCDHA1 PCDHA10 PCDHA11 PCDHA12 PCDHA13 PCDHA2 PCDHA3 PCDHA4 PCDHA5 PCDHA6 PCDHA7 PCDHA8 PCDHA9 PCDHAC1 PCDHAC2 PCDHB1 PCDHB10 PCDHB11 PCDHB12 PCDHB13 PCDHB14 PCDHB15 PCDHB16 PCDHB2 PCDHB3 PCDHB4 PCDHB5 PCDHB6 PCDHB7 PCDHB8 PCDHB9 PCDHGA1 PCDHGA10 PCDHGA11 PCDHGA12 PCDHGA2 PCDHGA3 PCDHGA4 PCDHGA5 PCDHGA6 PCDHGA7 PCDHGA8 PCDHGA9 PCDHGB1 PCDHGB2 PCDHGB3 PCDHGB4 PCDHGB5 PCDHGB6 PCDHGB7 PCDHGC3 PCDHGC4 PCDHGC5 PDGFRA PDGFRB PKP1 PKP2 PKP3 PPP1CA PPP1CB PPP1CC PPP1R1B PRICKLE1 PRICKLE2 PRICKLE3 PRICKLE4 PSEN1 PSEN2 PSENEN PTK2 PTK2B RAC1 RAC2 RAC3 RAF1 RELA RERE RHOA ROCK1 ROCK2 RRAS RRAS2 RYK SAV1 SCN1B SCN2B SCN3B SCN4B SCN5A SHOC2 STK3 TAOK1 TAOK2 TAOK3 TCF7 TCF7L1 TCF7L2 TEAD1 TEAD2 TEAD3 TEAD4 TJP1 TMC1 TMC2 TMC3 TMC4 TMC5 TMC6 TMC7 TMC8 TMIE USH1C USH1G VANGL1 VANGL2 VASP VAV1 VAV2 VAV3 VCL VIM WASF1 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WTIP WWC1 WWTR1 YAP1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ