微丝骨架的调节

中文名称

微丝骨架的调节

通路描述

微丝骨架的调节由Rho家族GTP酶（Rho、Rac、Cdc42）、WASP/WAVE蛋白、cofilin/ADF和Arp2/3核化因子控制；该通路驱动细胞迁移、吞噬作用、胞质分裂和形态变化。

英文描述

Regulation of actin cytoskeleton is controlled by Rho-family GTPases (Rho, Rac, Cdc42), WASP/WAVE proteins, cofilin/ADF, and Arp2/3 nucleation factor; this pathway drives cell migration, phagocytosis, cytokinesis, and morphological changes.

所含基因

232 个基因

ABI2 ACTB ACTG1 ACTN1 ACTN4 ACTR2 ACTR3 ACTR3B ACTR3C AKT1 AKT2 AKT3 APC APC2 ARAF ARHGAP35 ARHGEF1 ARHGEF12 ARHGEF4 ARHGEF6 ARHGEF7 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L BAIAP2 BCAR1 BDKRB1 BDKRB2 BRAF BRK1 BUB1B-PAK6 C5 C6 C7 C8A C8B C8G C9 CDC42 CFL1 CFL2 CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRK CRKL CXCL12 CXCR4 CYFIP1 CYFIP2 CYRIA CYRIB DIAPH1 DIAPH2 DIAPH3 DOCK1 EGF EGFR ENAH EZR F2 F2R FGD1 FGD3 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FN1 GIT1 GNA12 GNA13 GNG12 GSN HRAS INS INSRR IQGAP1 IQGAP2 IQGAP3 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 KNG1 KRAS LIMK1 LIMK2 LPAR1 LPAR2 LPAR4 LPAR5 MAP2K1 MAP2K2 MAPK1 MAPK3 MOS MRAS MSN MYH10 MYH11 MYH14 MYH9 MYL10 MYL11 MYL12A MYL12B MYL2 MYL5 MYL7 MYL9 MYLK MYLK2 MYLK3 MYLK4 NCKAP1 NCKAP1L NRAS P3R3URF-PIK3R3 PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PFN1 PFN2 PFN3 PFN4 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIKFYVE PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PPP1CA PPP1CB PPP1CC PPP1R12A PPP1R12B PPP1R12C PTK2 PXN RAC1 RAC2 RAC3 RAF1 RDX RGCC RHOA ROCK1 ROCK2 RRAS RRAS2 SCIN SLC9A1 SOS1 SOS2 SPATA13 SRC SSH1 SSH2 SSH3 TIAM1 TMSB4X TMSB4Y VAV1 VAV2 VAV3 VCL WASF1 WASF2 WASL