马达蛋白
中文名称
通路描述
马达蛋白包括微管相关动力蛋白和驱动蛋白，它们运输货物沿细胞轨道移动，以及肌球蛋白马达移动与肌动蛋白相关的囊泡；马达蛋白基因的缺陷会导致神经退行性疾病和遗传性痉挛性截瘫。
英文描述
Cytoskeleton in muscle cells: specialized cytoskeletal architecture of striated muscle including sarcomere organization with thick (myosin) and thin (actin, troponin-tropomyosin) filaments; the dystrophin-glycoprotein complex links intracellular actin to extracellular matrix for force transmission.
所含基因
232 个基因
ACTA1
ACTB
ACTC1
ACTG1
ACTG2
ACTN2
ACTN3
AGRN
AMPD1
AMPD2
AMPD3
ANK2
ANK3
ANKRD1
ANKRD2
ANKRD23
ATP1A1
ATP1A2
ATP1A3
ATP1A4
ATP1B1
ATP1B2
ATP1B3
ATP1B4
BGN
CAPN3
CAPZA1
CAPZA2
CAPZA3
CAPZB
CKM
COL11A1
COL11A2
COL1A1
COL1A2
COL24A1
COL27A1
COL3A1
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL5A1
COL5A2
COL5A3
COL6A1
COL6A2
COL6A3
COL6A5
COL6A6
COL9A1
COL9A2
COL9A3
COMP
CSRP1
CSRP2
CSRP3
DAAM1
DAAM2
DAG1
DCN
DES
DIAPH1
DIAPH2
DIAPH3
DMD
DSC2
DSG2
DSP
DTNA
ELN
EMD
ENO1
ENO2
ENO3
FBLN1
FBLN2
FBN1
FBN2
FBN3
FHL1
FHL2
FHL3
FLNC
FMN2
FMNL1
FMNL2
FMNL3
FN1
HSPG2
INF2
ITGA1
ITGA10
ITGA11
ITGA2
ITGA2B
ITGA3
ITGA4
ITGA5
ITGA6
ITGA7
ITGA8
ITGA9
ITGAV
ITGB1
ITGB3
ITGB4
ITGB5
ITGB6
ITGB7
ITGB8
JUP
LAMA1
LAMA2
LBR
LDB3
LMNA
LMNB1
LMNB2
LMOD1
LMOD2
LMOD3
MYBPC1
MYBPC2
MYBPC3
MYBPH
MYBPHL
MYH1
MYH10
MYH11
MYH13
MYH14
MYH15
MYH2
MYH3
MYH4
MYH6
MYH7
MYH7B
MYH8
MYH9
MYL1
MYL11
MYL2
MYL3
MYL4
MYL5
MYL7
MYL9
MYOM1
MYOM2
MYOM3
MYOT
MYOZ1
MYOZ2
MYOZ3
MYPN
NEB
NEBL
NID1
NID2
NRAP
OBSCN
PDLIM1
PDLIM2
PDLIM3
PDLIM4
PDLIM5
PDLIM7
PKP2
PLEC
SDC1
SDC2
SDC3
SDC4
SGCA
SGCB
SGCD
SGCE
SGCG
SGCZ
SNTA1
SNTB1
SNTB2
SPTAN1
SPTBN1
SPTBN2
SPTBN4
SPTBN5
SSPN
SUN1
SUN2
SYNE1
SYNE2
SYNE3
SYNPO2
TCAP
THBS1
THBS2
THBS3
THBS4
TLN1
TLN2
TMEM43
TMOD1
TMOD2
TMOD3
TMOD4
TNNC1
TNNC2
TNNI1
TNNI2
TNNI3
TNNT1
TNNT2
TNNT3
TPM1
TPM2
TPM3
TPM4
TRIM54
TRIM55
TRIM63
TTN
VCAN
VCL
VIM
XIRP1
XIRP2
ZYX