矿物质吸收
中文名称
通路描述
矿物质是维持生命所必需的五大基本营养素之一。钙在人体中发挥着无数作用,作为骨骼的主要成分,同时也是肌肉收缩/放松、神经网络、免疫系统和内分泌/外分泌细胞中的细胞内信使。铁、铜和其他金属对于氧化还原反应(作为辅因子)以及氧气运输和结合(在血红蛋白和肌红蛋白中)是必需的。许多酶需要特定的金属原子来完成催化功能。动物组织需要中等量的某些元素(Ca, P, K, Na, Mg, S, 和 Cl)以及微量量的其他元素(Mn, Fe, I, Co, Cr, Cu, Zn, 和 Se)。矿物质通过被动或主动转运系统穿过肠道黏膜吸收,通常使用专门的转运蛋白,如铁蛋白用于 Fe3+ 和维生素 D 诱导蛋白用于钙。
英文描述
Minerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an intracellular messenger in muscle contraction/relaxation, neural networks, the immune system, and endocrine/exocrine cells. Iron, copper, and other metals are required for redox reactions (as cofactors) and for oxygen transport and binding (in hemoglobin and myoglobin). Many enzymes require specific metal atoms to complete their catalytic functions. Animal tissues need moderate quantities of some elements (Ca, P, K, Na, Mg, S, and Cl) and trace amounts of others (Mn, Fe, I, Co, Cr, Cu, Zn, and Se). The minerals are absorbed by either passive or active transport systems through the intestinal mucosa, often using specialized transport proteins, such as ferritin for Fe3+ and vitamin D-induced protein for calcium.
所含基因
61 个基因
ATOX1
ATP1A1
ATP1A2
ATP1A3
ATP1A4
ATP1B1
ATP1B2
ATP1B3
ATP1B4
ATP2B1
ATP2B2
ATP2B3
ATP2B4
ATP7A
ATP7B
CLCN2
CYBRD1
FTH1
FTL
FXYD2
HEPH
HEPHL1
HMOX1
HMOX2
LOC107984936
MT1A
MT1B
MT1E
MT1F
MT1G
MT1H
MT1HL1
MT1M
MT1X
MT2A
S100G
SLC11A2
SLC26A3
SLC26A6
SLC26A9
SLC30A1
SLC31A1
SLC34A1
SLC34A2
SLC34A3
SLC39A4
SLC40A1
SLC46A1
SLC5A1
SLC6A19
SLC8A1
SLC8A2
SLC8A3
SLC9A3
STEAP1
STEAP2
TF
TRPM6
TRPM7
TRPV6
VDR