幽门螺杆菌感染中的上皮细胞信号
中文名称
通路描述
H. pylori 的两个主要毒力因子是溶酶体破坏毒素（VacA）和 C 型 IV 分泌系统（T4SS）及其转运的效应蛋白，细胞毒性相关抗原 A（CagA）。
英文描述
Two major virulence factors of H. pylori are the vacuolating cytotoxin (VacA) and the cag type-IV secretion system (T4SS) and its translocated effector protein, cytotoxin-associated antigen A (CagA).
所含基因
71 个基因
ADAM10
ADAM17
ATP6AP1
ATP6V0A1
ATP6V0A2
ATP6V0A4
ATP6V0B
ATP6V0C
ATP6V0D1
ATP6V0D2
ATP6V0E1
ATP6V0E2
ATP6V1A
ATP6V1B1
ATP6V1B2
ATP6V1C1
ATP6V1C2
ATP6V1D
ATP6V1E1
ATP6V1E2
ATP6V1F
ATP6V1G1
ATP6V1G2
ATP6V1G3
ATP6V1H
CASP3
CCL5
CDC42
CHUK
CSK
CXCL1
CXCL2
CXCL3
CXCL8
CXCR1
CXCR2
EGFR
F11R
GIT1
HBEGF
IGSF5
IKBKB
IKBKG
JAM2
JAM3
JUN
LOC101927180
LYN
MAP2K4
MAP3K14
MAPK10
MAPK11
MAPK12
MAPK13
MAPK14
MAPK8
MAPK9
MET
NFKB1
NFKBIA
NOD1
PAK1
PLCG1
PLCG2
PTPN11
PTPRZ1
RAC1
RELA
SRC
TCIRG1
TJP1